Alpine Immune Sciences has been acquired by Vertex

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A Unique Approach
to Immunology

Alpine Immune Sciences is a clinical stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies. Launched in 2015, we have created and advanced multiple product candidates into clinical trials for inflammatory/autoimmune diseases and cancer, formed collaborations with world-class partners, and built a robust development pipeline.

Our scientific platform consists of unique protein engineering strategies, including the directed evolution of immune proteins into novel, multi-targeted therapeutics. With such differentiated candidates, we hope to improve outcomes in patients with severe inflammatory and autoimmune diseases.

Join us in the discovery and development of next-generation immunotherapies.

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Alpine’s Pipeline

We have a diverse pipeline targeting autoimmune and inflammatory diseases. For more information on our ongoing clinical trials please refer to the clinical trials portion of our website. For additional information please refer to our corporate filingscorporate presentations, and scientific publications.

Acazicolcept (ALPN-101)

Dual CD28/ICOS Costimulation Antagonist

Autoimmune Diseases

Povetacicept (ALPN-303)

Dual BAFF/APRIL B cell cytokine antagonist

Autoimmune Diseases